By Sergey Uhanov (Certified Veterinarian)Dr. Sergey Uhanov Last updated: 31st January 2024



Sergey Uhanov (Certified Veterinarian) Dr. Sergey Uhanov
Last updated: 31st January 2024

The Daniff is a designer mix of the Great Dane and one of the many Mastiff breeds. The Bullmastiff or the English Mastiff is usually the standard choice in the US. Other countries may also use the Italian Mastiff or the Cane Corso. This gentle giant is well-loved among enthusiasts with its characteristic jowls, massive droopy ears, robust and muscular tail, and graceful gait.

Daniff Pictures

Quick Information

Other namesMastidane, Great Daniff, English Daniff
CoatShort and smooth
ColorFawn, brindle, black, blue, or white with possible harlequin or merle pattern
Breed typeCrossbred
Group Companion
Life expectancy8 – 12 years
HeightMale – 30 – 35 inches
Female – 23 – 28 inches
WeightMale – 115 – 150 pounds
Female – 115 – 125 pounds
Litter Size6 – 8 puppies
Behavioral Characteristics Affectionate, energetic, protective, intelligent, and loyal
Good with children Yes
Barking Tendency Low; they only bark when excited or suspicious
Climate compatibilityModerate; they are ill-suited for extreme temperatures
Apartment compatibilityLow; they prefer vast open fields or yards
Do they shedThey are low-shedders
Are they hypoallergenicNo
TrainabilityModerate; they tend to be stubborn
How much do they cost$1,000–$2,000
Competitive Registration Qualification/InformationDRA, IDCR, ACHC
CountryUnited States of America

History and Origin

These dogs likely appeared first in the United States around ten to fifteen years ago. The exact details of their conception are unknown, and their rich bloodline history indicates they may be older than previously thought. Despite this, they quickly gained popularity, to the extent that some pups find themselves abandoned in shelters today. As a crossbreed, eminent organizations like the AKC and FCI do not recognize them. However, owners can register their pets with clubs such as the American Canine Hybrid Club, the Designer Dogs Kennel Club, the Designer Breed Registry, the Dog Registry of America, Inc., the Daniff Kennel Club, and the International Designer Canine Registry.

Temperament and Personality

Despite their massive stature, these hybrids are loving, calm, gentle, and content to lay beside their owner and drool over them. They get along brilliantly with other pets and family members. However, one must be careful around young kids due to their size. Incredibly loyal and protective, they make excellent watchdogs by barking in the presence of unfamiliar people. Apartments and cramped living spaces can make them claustrophobic, and they do best in spacious homes with access to a fenced yard. Still, one should not leave them outside for long as they are primarily indoor dogs and can suffer from separation anxiety.

Like the Great Dane, their excellent memory and loyalty can make them unforgiving and forceful. A proper upbringing is necessary to curb territorial traits and undesirable behaviors like resource guarding. A well-trained pup becomes an obedient, faithful, and sincere companion.



They need at least ninety minutes of vigorous daily exercise to remain healthy. Long walks and activities like jogging, biking, and hiking are great options to explore together. Letting them run off-leash in a field or a dog park is an excellent way to release pent-up energy. Once tired out, they are happy to laze around and nap. Mental stimulation via games, toys, and puzzles is essential to avoid restlessness and aggression.


Their short, low-shedding coats are easy to groom. Brushing once or twice every week is enough for maintenance, though you may need to comb more frequently during their seasonal shed. Ensure you thoroughly wipe and dry their facial wrinkles to avoid bacterial growth. Clean their sizeable, floppy ears periodically, as they are prone to infections. Trim their nails when necessary and maintain adequate dental hygiene.

Health Problems

As crossbreeds, they can inherit several conditions from their parents. Some of them are joint dysplasia, arthritis, hypertrophic osteodystrophy, dilated cardiomyopathy, aortic stenosis, thyroid issues, eye problems, GDV or bloat, or various cancers. Of these, bloat is the most common ailment and can become life-threatening without timely medical intervention.


Fix their diet for a massive dog with medium energy levels. Around three cups of high-quality dry food in multiple feedings is enough for an adult. Adjust the kibble quantity if you include canned or wet food to prevent overfeeding. Also, ensure they don’t eat too quickly, which can increase the bloating risk. Lastly, always provide plenty of clean and fresh water.


These highly intelligent hybrids can be stubborn and wilful, making training challenging for novices. However, these rapid learners are eager to please, requiring patience and consistency for the best results.

Socialization: Start socializing your pup as soon as possible to ensure they get along with other household pets and strangers. Puppy classes and taking them to the park are splendid ways to remove shyness and wariness. They react best to positive reinforcement techniques with plenty of praise and rewards.

Obedience: Properly training them is even more crucial due to their enormous proportions, as handling an untrained dog of that size can become difficult. Be assertive and patient, keeping sessions short and engaging to prolong their interest. Hiring a professional if you need help teaching them yourself can be beneficial.

Interesting Facts

  • The International Organization of Hybrid or Crossbred Dogs and the International Designer Canine Registry officially recognized them in 2009.


1. What is the difference between a Daniff and a Great Dane?

Apart from being one of its parent lines, the Great Dane is slightly smaller and shorter-lived than the Daniff.

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